Name
  
Resource Date
  
Resource Type
  
Presenter/Author
  
Affiliation
  
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Resource_Description
  
  
11/21/2025Grand RoundsLaura Galuchie; Zachary SmithTufts University; Tufts Center for the Study of Drug Development (CSDD); Merck ＆ Co, Inc.TransCelerate and Tufts CSDD Uncover Opportunities to Rethink Data Collection and Optimize Protocol DesignLaura Galuchie and Zachary Smith discuss “TransCelerate and Tufts CSDD Uncover Opportunities to Rethink Data Collection and Optimize Protocol Design.”
  
11/21/2025Grand RoundsLaura Galuchie; Zachary SmithMerck ＆ Co, Inc.; Tufts University; Tufts Center for the Study of Drug Development (CSDD)TransCelerate and Tufts CSDD Uncover Opportunities to Rethink Data Collection and Optimize Protocol DesignLaura Galuchie and Zachary Smith discuss “TransCelerate and Tufts CSDD Uncover Opportunities to Rethink Data Collection and Optimize Protocol Design.”
  
11/14/2025Grand RoundsMark SiednerHarvard Medical School; Africa Health Research InstituteIMPACT-BP: A Community-Based Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South AfricaDr. Mark Siedner discusses “IMPACT-BP: A Community-Based Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South Africa.”
  
11/14/2025Grand RoundsMark SiednerHarvard Medical School; Africa Health Research InstituteIMPACT-BP: A Community-Based Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South AfricaDr. Mark Siedner discusses “IMPACT-BP: A Community-Based Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South Africa.”
  
11/7/2025Grand RoundsDaniel Pach; Stefanie LyskCharité – Universitätsmedizin BerlinEMMA – A Remote, Decentralized Clinical Trial to Evaluate the Effectiveness of a Migraine AppDaniel Pach and Stefanie Lysk discuss “EMMA – A Remote, Decentralized Clinical Trial to Evaluate the Effectiveness of a Migraine App.”
  
11/7/2025Grand RoundsDaniel Pach; Stefanie LyskCharité – Universitätsmedizin BerlinEMMA – A Remote, Decentralized Clinical Trial to Evaluate the Effectiveness of a Migraine AppDaniel Pach and Stefanie Lysk discuss “EMMA – A Remote, Decentralized Clinical Trial to Evaluate the Effectiveness of a Migraine App.”
  
10/31/2025Grand RoundsPeter Margolis; Sarah Greene; Sean C. DowdyStanford University; University of Cincinnati; Mayo Clinic; Cincinnati Children's Hospital Medical Center; The National Academy of MedicineThe LHS Shared Commitments — All Treats, No TricksPeter Margolis, Sean Dowdy, and Sarah Greene discuss “The LHS Shared Commitments – All Treats, No Tricks.”
  
10/31/2025Grand RoundsPeter Margolis; Sarah Greene; Sean C. DowdyUniversity of Cincinnati; Cincinnati Children's Hospital Medical Center; Mayo Clinic; Stanford University; The National Academy of MedicineThe LHS Shared Commitments — All Treats, No TricksPeter Margolis, Sean Dowdy, and Sarah Greene discuss “The LHS Shared Commitments – All Treats, No Tricks.”
  
10/24/2025Grand RoundsRenato LopesDuke Clinical Research Institute; Duke University Health SystemPrevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF TrialDr. Renato Lopes discusses “Prevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF Trial.”
  
10/24/2025Grand RoundsRenato LopesDuke University Health System; Duke Clinical Research InstitutePrevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF TrialDr. Renato Lopes discusses “Prevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF Trial.”
  
10/17/2025Grand RoundsKeith Marsolo; Charles BaileyUniversity of Pennsylvania; Children's Hospital of Philadelphia; Duke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Making Effective Use of Data Infrastructure in PCORnet®Drs. Charles Bailey and Keith Marsolo discuss “Making Effective Use of Data Infrastructure in PCORnet®.”
  
10/17/2025Grand RoundsCharles Bailey; Keith MarsoloUniversity of Pennsylvania; Children's Hospital of Philadelphia; Duke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Making Effective Use of Data Infrastructure in PCORnet®Drs. Charles Bailey and Keith Marsolo discuss “Making Effective Use of Data Infrastructure in PCORnet®.”
  
10/10/2025Grand RoundsJulie Fritz; Sebastian TongUniversity of Utah; University of WashingtonIntegrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health InitiativeDrs. Fritz and Tong discuss "Integrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health Initiative."
  
10/10/2025Grand RoundsJulie Fritz; Sebastian TongUniversity of Utah; University of WashingtonIntegrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health InitiativeDrs. Fritz and Tong discuss "Integrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health Initiative."
  
10/3/2025Grand RoundsElisabetta TonetUniversitaria di FerraraMulti-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe TrialDr. Elisabetta Tonet discusses “Multi-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe Trial.”
  
10/3/2025Grand RoundsElisabetta TonetUniversitaria di FerraraMulti-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe TrialDr. Elisabetta Tonet discusses “Multi-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe Trial.”
  
9/26/2025Grand RoundsElizabeth Turner; Gregory Simon; Susan HuangKaiser Permanente Washington Health Research Institute; University of California, Irvine; Duke UniversitySignificance in ePCTs: P Values vs Decision-Maker PerspectivesDrs. Gregory Simon, Susan Huang, and Elizabeth Turner discuss “Significance in ePCTs: P Values vs Decision-Maker Perspectives.”
  
9/26/2025Grand RoundsElizabeth Turner; Gregory Simon; Susan HuangKaiser Permanente Washington Health Research Institute; University of California, Irvine; Duke UniversitySignificance in ePCTs: P Values vs Decision-Maker PerspectivesDrs. Gregory Simon, Susan Huang, and Elizabeth Turner discuss “Significance in ePCTs: P Values vs Decision-Maker Perspectives.”
  
9/19/2025Grand RoundsDenise van HoutUniversity Medical Center Utrecth, the NetherlandsHurdles for the Delivery of Clinical Trials: Insights From the REMAP-CAP Trial in EuropeDr. Denise van Hout discusses the factors that led to success and challenges in different REMAP-CAP study sites.
  
9/19/2025Grand RoundsDenise van HoutUniversity Medical Center Utrecth, the NetherlandsHurdles for the Delivery of Clinical Trials: Insights From the REMAP-CAP Trial in EuropeDr. Denise van Hout discusses the factors that led to success and challenges in different REMAP-CAP study sites.
  
9/5/2025Grand RoundsRobert CaliffDuke University School of MedicineThe Non-Learning Health SystemDr. Robert Califf discusses the non-learning health system.
  
8/22/2025Grand RoundsEmily O'BrienDuke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical TrialsDr. Emily O’Brien discusses “Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical Trials.”
  
8/22/2025Grand RoundsEmily O'BrienPatient-Centered Outcomes Research Institute (PCORI); Duke University School of Medicine; Duke Clinical Research InstituteAvoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical TrialsDr. Emily O’Brien discusses “Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical Trials.”
  
8/15/2025Grand RoundsTim Walsh; Chris Weir; Richard ParkerUniversity of EdinburghDexmedetomidine- or Clonidine-Based Sedation Compared with Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial – Addressing a Complex Clinical Question with Novel Integrated Methodological ApproachesProfessors Tim Walsh and Chris Weir and Research Fellow Richard Parker discuss the A2B trial of dexmedetomidine- or clonidine-based sedation compared with propofol for critically ill patients.
  
8/15/2025Grand RoundsTim Walsh; Chris Weir; Richard ParkerUniversity of EdinburghDexmedetomidine- or Clonidine-Based Sedation Compared with Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial – Addressing a Complex Clinical Question with Novel Integrated Methodological ApproachesProfessors Tim Walsh and Chris Weir and Research Fellow Richard Parker discuss the A2B trial of dexmedetomidine- or clonidine-based sedation compared with propofol for critically ill patients.
  
8/8/2025Grand RoundsA. Eden EvinsHarvard Medical School; Massachusetts General HospitalYouth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting SupportDr. Eden Evins discusses “Youth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting Support."
  
8/8/2025Grand RoundsA. Eden EvinsHarvard Medical School; Massachusetts General HospitalYouth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting SupportDr. A. Eden Evins discusses “Youth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting Support."
  
8/1/2025Grand RoundsKenneth KehlDana-Farber Cancer InstituteClinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer ProgressionDr. Kenneth L. Kehl discusses “Clinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer Progression.”
  
8/1/2025Grand RoundsKenneth KehlDana-Farber Cancer InstituteClinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer ProgressionDr. Kenneth L. Kehl discusses “Clinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer Progression.”
  
7/18/2025Grand RoundsAdrian Hernandez; Christopher Lindsell; Karen Chiswell; Sara Calvert; Rebecca SullengerDuke Clinical Research Institute; Duke University School of Medicine; Clinical Trials Transformation Initiative (CTTI)State of Clinical Trials: An Analysis of ClinicalTrials.govAdrian Hernandez, Rebecca Sullenger, Sara Bristol Calvert, Karen Chiswell, and Christopher Lindsell discuss the state of clinical trials.
  
7/18/2025Grand RoundsAdrian Hernandez; Christopher Lindsell; Karen Chiswell; Sara Calvert; Rebecca SullengerDuke Clinical Research Institute; Duke University School of Medicine; Clinical Trials Transformation Initiative (CTTI)State of Clinical Trials: An Analysis of ClinicalTrials.govAdrian Hernandez, Rebecca Sullenger, Sara Bristol Calvert, Karen Chiswell, and Christopher Lindsell discuss the state of clinical trials.
  
7/11/2025Grand RoundsTrevor Lentz; Tyler CopeDuke Clinical Research Institute; Duke University; Veterans Health AdministrationNovel Approaches to Recruiting Clinical Sites for Embedded Pragmatic Clinical Trials: Insights from the AIM-Back TrialDr. Trevor Lentz and Tyler Cope discuss the novel approaches used for site recruitment in the AIM-back Trial.
  
7/11/2025Grand RoundsTrevor Lentz; Tyler CopeDuke Clinical Research Institute; Duke University; Veterans Health AdministrationNovel Approaches to Recruiting Clinical Sites for Embedded Pragmatic Clinical Trials: Insights from the AIM-Back TrialDr. Trevor Lentz and Tyler Cope discuss the novel approaches used for site recruitment in the AIM-back Trial.
  
6/27/2025Grand RoundsAmrita MukhopadhyayNYU Langone Health; New York University School of MedicineGR-Slides-06-27-25Dr. Amrita Mukhopadhyay discusses "Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)."
  
6/27/2025Grand RoundsAmrita MukhopadhyayNew York University School of Medicine; NYU Langone HealthBuilding Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)Dr. Amrita Mukhopadhyay discusses "Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)."
  
6/20/2025Grand RoundsScott GarrisonUniversity of Alberta; Pragmatic Trials CollaborativeThe BedMed Trials: Does the Timing of Blood Pressure Medication Matter?Dr. Scott Garrison discusses the BedMed Trials: Does the Timing of Blood Pressure Medication Matter?
  
6/20/2025Grand RoundsScott GarrisonUniversity of Alberta; Pragmatic Trials CollaborativeThe BedMed Trials: Does the Timing of Blood Pressure Medication Matter?Dr. Scott Garrison discusses the BedMed Trials: Does the Timing of Blood Pressure Medication Matter?
  
6/13/2025Grand RoundsNancy Kass; Ruth Faden; Stephanie Morain; Stephanie MorainJohns Hopkins University; Johns Hopkins Berman Institute of BioethicsFit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical TrialsDrs. Morain, Kass, and Faden discuss “Fit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical Trials.”
  
6/13/2025Grand RoundsNancy Kass; Stephanie Morain; Stephanie Morain; Ruth FadenJohns Hopkins Berman Institute of Bioethics; Johns Hopkins UniversityFit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical TrialsDrs. Morain, Kass, and Faden discuss “Fit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical Trials.”
  
6/6/2025Grand RoundsJonathan CaseyVanderbilt University; Pragmatic Clinical Care Research GroupThe REDCap Advanced Randomization Module: A Trial Innovation Network Project to Support the Needs of Modern TrialsDr. Jonathan D. Casey discusses the REDCap advanced randomization module: a trial innovation network project to support the needs of modern trials.
  
6/6/2025Grand RoundsJonathan CaseyVanderbilt University; Pragmatic Clinical Care Research GroupThe REDCap Advanced Randomization Module: A Trial Innovation Network Project to Support the Needs of Modern TrialsDr. Jonathan D. Casey discusses the REDCap advanced randomization module: a trial innovation network project to support the needs of modern trials.
  
5/30/2025Grand RoundsAnkeet BhattKaiser Permanente Northern California; Stanford UniversityEmbedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE TrialDr. Ankeet S. Bhatt discusses “Embedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE Trial.”
  
5/30/2025Grand RoundsAnkeet BhattKaiser Permanente Northern California; Stanford UniversityEmbedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE TrialDr. Ankeet S. Bhatt discusses “Embedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE Trial.”
  
5/16/2025Grand RoundsAdrian Hernandez; Jeffrey SpaederDuke Clinical Research InstituteGrand Rounds May 16, 2025: Pivoting Clinical Trials Into a New and Evolving World (Jeffrey A. Spaeder, MD; Adrian F. Hernandez, MD, MHS)Drs. Jeffrey Spaeder and Adrian Hernandez discuss “Pivoting Clinical Trials Into a New and Evolving World.”
  
5/16/2025Grand RoundsAdrian Hernandez; Jeffrey SpaederDuke Clinical Research Institute; IQVIAGrand Rounds May 16, 2025: Pivoting Clinical Trials Into a New and Evolving World (Jeffrey A. Spaeder, MD; Adrian F. Hernandez, MD, MHS)Drs. Jeffrey Spaeder and Adrian Hernandez discuss “Pivoting Clinical Trials Into a New and Evolving World.”
  
5/2/2025Grand RoundsRoland RJ van KimmenadeRadboud University Medical CenterFluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP StudyDr. Roland RJ van Kimmenade discusses “Fluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP Study.”
  
5/2/2025Grand RoundsRoland RJ van KimmenadeRadboud University Medical CenterFluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP StudyDr. Roland RJ van Kimmenade discusses “Fluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP Study.”
  
4/25/2025Grand RoundsMing Tai-SealeUniversity of California, San DiegoAutomated Response Technology Integrated into EMR and Physician-Patient CommunicationDr. Ming Tai-Seale discusses “Automated Response Technology Integrated into EMR and Patient-Physician Communication.”
  
4/25/2025Grand RoundsMing Tai-SealeUniversity of California, San DiegoAutomated Response Technology Integrated into EMR and Physician-Patient CommunicationDr. Ming Tai-Seale discusses “Automated Response Technology Integrated into EMR and Patient-Physician Communication.”
  
4/18/2025Grand RoundsSanjit S. JollyMcMaster UniversityColchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 TrialDr. Sanjit S. Jolly discusses “Colchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 Trial.”
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