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Welcome to the Knowledge Repository, a searchable collection of resources related to pragmatic clinical trials, compiled by the NIH Collaboratory Coordinating Center. For additional content and information about the NIH Collaboratory, visit www.rethinkingclinicaltrials.org.

  
  
  
  
  
  
Getting the Right Evidence to Decision-Makers Faster: Insights From the NIH Pragmatic Trials Collaboratory A VIRTUAL WORKSHOP5/31/2023HandoutWorkshop flyer
  
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture5/19/2023Grand RoundsDr. Robert O’Toole discusses the pragmatic trial Aspirin vs. Low Molecular Weight Heparin for Thromboprophylaxis: A Randomized Clinical Trial of Over 12,000 Orthopedic Trauma Patients.
  
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture5/19/2023Grand RoundsDr. Robert O’Toole discusses the pragmatic trial Aspirin vs. Low Molecular Weight Heparin for Thromboprophylaxis: A Randomized Clinical Trial of Over 12,000 Orthopedic Trauma Patients.
  
Adrian Hernandez Presentation 2023 Steering Committee Meeting5/17/2023PresentationAdrian Hernandez's presentation on clinical decision support software in ePCTs at the 2023 Steering Committee meeting.
  
FDA Presentation 2023 Steering Committee Meeting5/17/2023PresentationMatthew Diamond and Sonja Fulmer present on the FDA approach to clinical decision support (CDS) software at the 2023 Steering Committee meeting.
  
Pearl O'Rourke Presentation 2023 Steering Committee Meeting5/17/2023PresentationPearl O'Rourke discusses clinical decision software being defined as a device at the 2023 Steering Committee meeting.
  
Stacey Arnold Presentation 2023 Steering Committee Meeting5/17/2023PresentationStacey ARnold's presentation on NIH and other requirements for ClinicalTrials.gov reporting at the 2023 Steering Committee meeting.
  
Taunton Paine Presentation 2023 Steering Committee Meeting5/17/2023PresentationTuanton Paine's presentation on NIH data management and sharing policy at the 2023 Steering Committee meeting.
  
Keith Marsolo Presentation 2023 Steering Committee Meeting5/17/2023PresentationKeith Marsolo's presenation on clarifying different scientific goals and resources needed for data sharing at the 2023 Steering Committee meeting.
  
Kevin Weinfurt Lightning Round Presentation 2023 Steering Committee Meeting5/17/2023PresentationKevin Weinfurt's lightning round presentation at the 2023 Steering Committee meeting
  
Lynn DeBar Sharing Study Results Presentation 2023 Steering Committee Meeting5/17/2023PresentationLynn DeBar's panel presentation on sharing study results at the 2023 Steering Committee meeting
  
Emily O'Brien HERO Presentation 2023 Steering Committee Meeting5/17/2023PresentationEmily O'Brien's presentation on the HERO program experience at the 2023 Steering Committee meeting
  
Natalia Morone Presentation 2023 Steering Committee Meeting5/17/2023PresentationNatalia Morone's panel presentation on sharing results at the 2023 Steering Committee meeting
  
Stephanie Morain Presentation 2023 Steering Committee Meeting5/17/2023PresentationStephanie Morain's presentation on navigating ethical challenges when sharing data for ePCTs at 2023 Steering Committee meeting
  
Adrian Hernandez Data Sharing Presentation 2023 Steering Committee Meeting5/17/2023PresentationAdrian Hernandez's presentation on how to drive change in the incentive structure to promote data sharing at the 2023 Steering Committee meeting
  
Lynn DeBar Back in Action Presentation 2023 Steering Committee Meeting5/17/2023PresentationLynn DeBar presents on barriers and challenges of Back in Action at the 2023 Steering Committee meeting
  
Julie Fritz BeatPain Utah Presentation 2023 Steering Committee Meeting5/17/2023PresentationJulie Fritz discusses the challenges and barriers of the BeatPain Utah trial at the 2023 Steering Committee meeting
  
Kathleen Sluka FM-TIPS Presentation 2023 Steering Committee Meeting5/17/2023PresentationKathleen Sluka discusses the challenges and barriers of the FM-TIPS trial at the 2023 Steering Committee meeting
  
Ardith Doorenbos Presentation 2023 Steering Committee Meeting 5/17/2023PresentationArdith Doorenbos discusses the challenges and barriers of the GRACE trial at the 2023 Steering Committee meeting
  
NOHARM Presentation 2023 Steering Committee meeting5/17/2023PresentationAndrea Chiville and Jon Tilburt share the challenges and barriers of the NOHARM trial at the 2023 Steering Committee meeting
  
Natalia Morone OPTIMUM Presentation 2023 Steering Committee Meeting5/17/2023PresentationNatalia Morone shares challenges and barriers of OPTIMUM study at the 2023 Steering Committee meeting
  
eBooklet 2023 SC Mtg_Final5/16/2023
  
2023 Steering Committee Meeting Agenda5/16/2023AgendaAgenda for the 2023 NIH Pragmatic Trials Collaboratory Steering Committee Meeting.
  
2023 Steering Committee Participant List5/16/2023Participant ListList of participants from the NIH Pragmatic Trials Collaboratory 2023 Steering Committee Meeting.
  
David Chamber Keynote Panel at 2023 Steering Committee Meeting 5/16/2023PresentationDr. David Chambers delivered the Keynote Panel on the role of implementation science in ePCTs.
  
PROVEN Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Vincent Mor's panel presnetation on video intervention efforts for the PROVEN trial.
  
Lynn DeBar Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Lynn DeBar's panel presentation on implemenatation learnings from PPACT
  
Steven George and Lindsay Ballengee Presentation at 2023 Steering Committee Meeting5/16/2023PresentationSteven George and Lindsay Ballengee present on the intervention complexity tool at the 2023 Steering Committee meeting
  
Kevin Weinfurt presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Kevin Weinfurt and panel discuss cross-core collaborations.
  
Eliseo Perez-Stable Keynote Address 2023 Steering Committee Meeting5/16/2023PresentationDr. Eliseo Perez-Stable delivers a keynote address on communitiy engaged research and the pathway to reducing disparities
  
Rosa Gonzalez-Guarda Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Gonzalez-Guarda moderates a panel discussion on health equity.
  
Julie Fritz Panel Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Fritz discusses nonpharmacologic pain management in federally qualified health center primary care clinics through the BeatPain Utah trial.
  
Corita Grudzen Panel Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Grudzen speaks on the Health Equity panel at the 2023 Steering Committee Meeting.
  
Michael Ho Panel Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Ho's presentation on the Health Equity panel at 2023 Steering Committee Meeting
  
Cherise Harrington Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Harrington moderates a panel discussion on health equity.
  
Diana Burgess Panel Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Burgess discusses justice and equity in PCTs at 2023 Steering Committee Meeting
  
Greg Simon Panel Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Simon's presentation on MHRN basics on the Focus on Health Equity panel at the 2023 Steering Committee meeting.
  
Ana Quinones Panel Presentation 2023 Steering Committee Meeting5/16/2023PresentationDr. Quinones provides an overview of health equity work in the Collaboratory at the 2023 Steering Committee meeting.
  
Anne Trontell Panel Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Trontell discusses PCORI's experience in advancing health equity in pragmatic research.
  
Shruti Gohil INSPIRE Presentation at 2023 Steering Committee Meeting5/16/2023PresentationShruti Gohil provides an update on INSPIRE.
  
Dr. Tulsky and Dr. Volandes Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Tulsky and Dr. Volandes discuss ACP PEACE challenges and barriers at 2023 Steering Committee Meeting
  
Stacy Sterling Presentation at 2023 Steering Committee Meeting5/16/2023PresentationStacy Sterling speaks on challenges and barriers of GGC4H at the 2023 Steering Committee meeting
  
Hrishikesh Chakraborty Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Chakraborty presents on challenges and barriers of the HiLo trial at the 2023 Steering Committee meeting
  
Miguel Vazquez Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Vazquez discuesses challenges and barriers of ICD-Pieces trial at 2023 Steering Committee meeting.
  
Christine Goertz Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Goertz speaks on challenges and barriers of IMPACt-LBP trial at 2023 Steering Committee Meeting
  
Michael Ho & Sheana Bull Presentation 2023 Steering Committee Meeting5/16/2023PresentationMichael Ho and Sheana Bull speak on the Nudge study at the 2023 Steering Committee meeting
  
Corita Grudzen Presentation at 2023 Steering Committee Meeting5/16/2023PresentationDr. Grudzen presents on challenges and barriers of PRIM-ER trial at 2023 Steering Committee meeting
  
May 15, 2023: EMBED Offers Lessons for Intervention Adoption, Implementation, and Maintenance5/15/2023News article
  
Developing an implementation blueprint for the NIH HEAL Initiative GRACE trial: perspectives on acupuncture and guided relaxation for chronic sickle cell disease pain5/15/2023Journal articlePublication from the GRACE Demonstration Project
  
Design and Pragmatic Trial of COACH: A Patient Portal/EHR Information System for Home Blood Pressure Monitoring in Hypertension5/12/2023Grand RoundsDr. Richelle Koopman discusses Design and Pragmatic Trial of COACH: A Patient Portal/EHR Information System for Home Blood Pressure Monitoring.
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