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Welcome to the Knowledge Repository, a searchable collection of resources related to pragmatic clinical trials, compiled by the NIH Collaboratory Coordinating Center. For additional content and information about the NIH Collaboratory, visit www.rethinkingclinicaltrials.org.

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Assessment of the Human Systemic Absorption of Sunscreen Active Ingredients: FDA-Sponsored Randomized Clinical Trial1/17/2020Grand Rounds
  
Assessment of the Human Systemic Absorption of Sunscreen Active Ingredients: FDA-Sponsored Randomized Clinical Trial1/17/2020Video
  
Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening1/10/2020Grand Rounds
  
Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening1/10/2020Video
  
Statement by Individual Leaders and Investigators Involved in Pragmatic Clinical Trials Embedded in Healthcare Systems1/9/2020
  
Considerations for using distributed research networks to conduct aspects of randomized trials1/2/2020Journal article
  
Evaluation of a Level I trauma center provider training in alcohol brief intervention delivery within a 25-site trial of screening and intervention for PTSD and related comorbidity12/29/2019Journal article
  
EMBED Update: Challenges and Solutions12/13/2019Grand Rounds
  
EMBED Update: Challenges and Solutions12/13/2019Video
  
Principles and procedures for data and safety monitoring in pragmatic clinical trials12/9/2019Journal article
  
Millions More People, Stronger Collaborations: The New and Improved NIH Collaboratory Distributed Research Network12/6/2019Grand Rounds
  
Millions More People, Stronger Collaborations: The New and Improved NIH Collaboratory Distributed Research Network12/6/2019Video
  
PRIM-ER Study Snapshot12/5/2019Handout
  
Incidence of statin use in older adults with and without cardiovascular disease and diabetes mellitus, January 2008-March 201812/5/2019Journal article
  
Development and assessment of a crosswalk between ICD-9-CM and ICD-10-CM to identify patients with common pain conditions12/1/2019Journal article
  
Taking opioids in times of crisis: institutional oversight, chronic pain and suffering in an integrated healthcare delivery system in the U.S.12/1/2019Journal article
  
Understanding implementation fidelity in a pragmatic randomized clinical trial in the nursing home setting: a mixed-methods examination11/28/2019Journal article
  
ABATE Infection Closeout Snapshot11/22/2019Handout
  
It’s Time to Learn From Patients Like Mine11/22/2019Grand Rounds
  
It’s Time to Learn From Patients Like Mine11/22/2019Video
  
It’s Time to Learn From Patients Like Mine11/22/2019Podcast
  
AcuOA_Sherman_DeBar_PRISM Kickoff_FINAL111/19/2019Presentation
  
CC Overview_Hernandez_PRISM Kickoff_Final111/19/2019Presentation
  
ClinicalTrials_gov_Stacey Arnold_PRISM Kickoff_Final111/19/2019Presentation
  
CMS_Chin_PRISM Kickoff_Final111/19/2019Presentation
  
Collaboratory PRISM Kick Off Meeting Agenda_19NOV2019_Final111/19/2019Agenda
  
FM TIPS_Sluka_Crofford_PRISM Kickoff_FINAL111/19/2019Presentation
  
HEAL Cooperative Agreement_Weber _Wandner_PRISM Kickoff_Final111/19/2019Presentation
  
HEAL Initiative_Baker_PRISM Kickoff_Final111/19/2019Presentation
  
NOHARM_Cheville_Tilburt_PRISM Kickoff_Final111/19/2019Presentation
  
OPTIMUM_Morone_PRISM Kickoff_FINAL111/19/2019Presentation
  
Overview_Meyers_ PRISM Kickoff_Final111/19/2019Presentation
  
Particpant list_PRISM Kickoff Meeting_NOV2019_Post Meeting111/19/2019Participant List
  
PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks11/15/2019Grand Rounds
  
PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks11/15/2019Video
  
Lumbar Imaging with Reporting of Epidemiology: Initial Results and Some Lessons Learned11/8/2019Grand Rounds
  
Lumbar Imaging with Reporting of Epidemiology: Initial Results and Some Lessons Learned11/8/2019Video
  
Accelerating Evidence Generation in Nephrology11/8/2019Presentation
  
Opportunities for Embedded Pragmatic Trials in Nephrology11/8/2019Presentation
  
Design and Analysis Strategies for Embedded Pragmatic Clinical Trials11/8/2019Presentation
  
Engaging Stakeholders and Aligning with Health System Partners11/8/2019Presentation
  
Designing for Post-Trial Implementation11/8/2019Presentation
  
Nudge Study Snapshot11/5/2019Handout
  
EMBED Study Snapshot11/5/2019Handout
  
GGC4H Study Snapshot11/5/2019Handout
  
ACP PEACE Study Snapshot11/5/2019Handout
  
NIH Collaboratory: Looking Back and Looking Forward11/1/2019Grand Rounds
  
NIH Collaboratory: Looking Back and Looking Forward11/1/2019Video
  
Pragmatic quality assessment of brief health behavior change interventions: evidence for criterion-related validity of the Behavior Change Counseling Index11/1/2019Journal article
  
Identifying opioid use disorder in the emergency department: multi-system electronic health record–based computable phenotype derivation and validation study10/31/2019Journal article
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