| HERO-TOGETHER: Building Vaccine Confidence With Long-Term Outcomes Data | 1/8/2021 | Grand Rounds | Dr. O’Brien discusses the HERO-TOGETHER initiative that aims to understand how healthcare workers do after receiving a COVID-19 vaccination. |
| HERO-TOGETHER: Building Vaccine Confidence With Long-Term Outcomes Data | 1/8/2021 | Grand Rounds | Dr. O’Brien discusses the HERO-TOGETHER initiative that aims to understand how healthcare workers do after receiving a COVID-19 vaccination. |
| FM TIPS Study Snapshot | 1/7/2021 | Handout | Study snapshot of the FM TIPS Demonstration Project |
| BackInAction Study Snapshot | 1/7/2021 | Handout | Study snapshot of the BackInAction Demonstration Project |
| NOHARM Study Snapshot | 1/7/2021 | Handout | Study snapshot of the NOHARM Demonstration Project |
| OPTIMUM Study Snapshot | 1/7/2021 | Handout | Study snapshot of the OPTIMUM Demonstration Project |
| The SAMSON Trial: An N-of-1 Trial of Statin, Placebo, and No Treatment to Assess Patient Symptoms | 12/18/2020 | Grand Rounds | Dr. Shun-Shin describes the design and results of the SAMSON trial that evaluated perceived side effects of statin medications. |
| The SAMSON Trial: An N-of-1 Trial of Statin, Placebo, and No Treatment to Assess Patient Symptoms | 12/18/2020 | Grand Rounds | Dr. Shun-Shin describes the design and results of the SAMSON trial that evaluated perceived side effects of statin medications. |
| December 15, 2020: A Year of Results and New Insights From the NIH Collaboratory | 12/15/2020 | News article | News article about NIH Collaboratory publications in 2020 |
| PREVENTABLE: Starting a Pragmatic Trial in a Pandemic | 12/11/2020 | Grand Rounds | Drs. Alexander and Jones describe the challenges of starting a trial during the COVID-19 pandemic. |
| PREVENTABLE: Starting a Pragmatic Trial in a Pandemic | 12/11/2020 | Grand Rounds | Drs. Alexander and Jones describe the challenges of starting a trial during the COVID-19 pandemic. |
| The Yale New Haven Health System as an Evidence Generation Ecosystem for Heart Failure | 12/4/2020 | Grand Rounds | Dr. Ahmad discusses studies evaluating data-driven methodologies for predicting clinical outcomes in patients with heart failure. |
| The Yale New Haven Health System as an Evidence Generation Ecosystem for Heart Failure | 12/4/2020 | Grand Rounds | Dr. Ahmad discusses studies evaluating data-driven methodologies for predicting clinical outcomes in patients with heart failure. |
| Drug Development in Kidney Disease: Proceedings from a Multi-Stakeholder Panel | 11/20/2020 | Grand Rounds | Dr. Edmonston describes the landscape of drug development and clinical trials evaluating treatments for chronic kidney disease. |
| Drug Development in Kidney Disease: Proceedings from a Multi-Stakeholder Panel | 11/20/2020 | Grand Rounds | Dr. Edmonston describes the landscape of drug development and clinical trials evaluating treatments for chronic kidney disease. |
| Pragmatic and Explanatory Attitudes to RCTs: Using the PRECIS-2 Tool to Describe the Design of the MyTEMP Trial | 11/13/2020 | Grand Rounds | Drs. Zwarenstein, Al-Jaishi, and Garg discuss the differences between explanatory and pragmatic approaches to randomized controlled trials as illustrated by two contrasting trials. |
| Pragmatic and Explanatory Attitudes to RCTs: Using the PRECIS-2 Tool to Describe the Design of the MyTEMP Trial | 11/13/2020 | Grand Rounds | Drs. Zwarenstein, Al-Jaishi, and Garg discuss the differences between explanatory and pragmatic approaches to randomized controlled trials as illustrated by two contrasting trials. |
| Reduction in movement-evoked pain and fatigue during initial 30-minute TENS treatment predicts TENS responders in women with fibromyalgia | 11/11/2020 | Journal article | Publication from the FM TIPS Demonstration Project |
| PROVEN Closeout Snapshot | 11/10/2020 | Handout | Closeout snapshot of the PROVEN Demonstration Project |
| 2020 PRISM Onboarding Meeting Agenda | 11/9/2020 | Agenda | Agenda for the November 9, 2020 PRISM Onboarding meeting. |
| Program Overview Presentation at 2020 PRISM Onboarding Meeting | 11/9/2020 | Presentation | Dr. Meyers gives an overview of the Collaboratory at the 2020 PRISM Onboarding Meeting. |
| HEAL Cooperative Agreement Presentation at 2020 PRISM Onboarding Meeting | 11/9/2020 | Presentation | Drs. Weber and Wandner give a presentation on the HEAL Cooperative Agreement at the 2020 PRISM Onboarding Meeting. |
| BeatPain Utah Presentation at 2020 PRISM Onboarding Meeting | 11/9/2020 | Presentation | Dr. Fritz presents on BeatPain Utah at the 2020 PRISM Onboarding Meeting. |
| HEAL Overview Presentation at the 2020 PRISM Onboarding Meeting | 11/9/2020 | Presentation | Dr. Baker gives a HEAL Overview at the 2020 PRISM Onboarding Meeting. |
| Participant List for 2020 PRISM Onboarding Meeting | 11/9/2020 | Participant List | List of participants for the 2020 PRISM Virtual Onboarding Meeting. |
| Impact of an advance care planning video intervention on care of short-stay nursing home patients | 11/7/2020 | Journal article | Publication from the PROVEN Demonstration Project |
| Appendectomy Versus Antibiotics for Appendicitis–Early Results from the CODA Trial | 11/6/2020 | Grand Rounds | Dr. Flum discusses the CODA comparative effectiveness trial that compared two treatments for appendicitis. |
| Appendectomy Versus Antibiotics for Appendicitis–Early Results from the CODA Trial | 11/6/2020 | Grand Rounds | Dr. Flum discusses the CODA comparative effectiveness trial that compared two treatments for appendicitis. |
| Lessons from Virtual Trials in Time of a Pandemic: Minnesota Hydroxychloroquine Experience | 11/6/2020 | Podcast | Dr. Boulware discusses the complexities of conducting virtual clinical trials during the COVID-19 pandemic. |
| Lessons from Virtual Trials in Time of a Pandemic: Minnesota Hydroxychloroquine Experience | 11/6/2020 | Transcript | Dr. Boulware discusses the complexities of conducting virtual clinical trials during the COVID-19 pandemic. |
| November 5, 2020: NIH HEAL Initiative Common Data Elements Published in the Living Textbook | 11/5/2020 | News article | News article about NIH HEAL common data elements |
| LIRE Closeout Snapshot | 11/5/2020 | Handout | Closeout snapshot of the LIRE Demonstration Project |
| November 3, 2020: Disseminating Trial Results: We Can Have Faster and Better | 11/3/2020 | News article | News article about speedier dissemination of trail results. |
| November 2, 2020: PRIM-ER Pilot Study Identifies Keys to Implementation Success | 11/2/2020 | News article | News article about PRIM-ER implementation publication. |
| Lessons from Virtual Trials in Time of a Pandemic: Minnesota Hydroxychloroquine Experience | 10/30/2020 | Grand Rounds | Dr. Boulware describes how his study team was able to rapidly set up virtual clinical trials during the early days of the COVID-19 pandemic. |
| Lessons from Virtual Trials in Time of a Pandemic: Minnesota Hydroxychloroquine Experience | 10/30/2020 | Grand Rounds | Dr. Boulware describes how his study team was able to rapidly set up virtual clinical trials during the early days of the COVID-19 pandemic. |
| Effectiveness and reach of the Primary Palliative Care for Emergency Medicine (PRIM-ER) Pilot Study: a qualitative analysis | 10/27/2020 | Journal article | Publication from the PRIM-ER Demonstration Project |
| Outpatient Clinical Decision Support – An Evidence-Based Implementation Framework | 10/23/2020 | Grand Rounds | Drs. Sperl-Hillen and O’Connor share lessons learned in the development of a clinical decision support system used in primary care visits. |
| Outpatient Clinical Decision Support – An Evidence-Based Implementation Framework | 10/23/2020 | Grand Rounds | Drs. Sperl-Hillen and O’Connor share lessons learned in the development of a clinical decision support system used in primary care visits. |
| October 22, 2020: TSOS Study Team Describes Impacts of a COVID-19 Surge on Delivery of Acute Care and Emergency Services | 10/22/2020 | News article | News article describing impacts of COVID on TSOS. |
| Rapid ethnographic assessment of the COVID-19 pandemic April 2020 'surge' and its impact on service delivery in an acute care medical emergency department and trauma center | 10/20/2020 | Journal article | Publication from the TSOS Demonstration Project |
| Back to School, It’s More Than Just a Trip to Target This Year: The ABC Science Collaborative | 10/16/2020 | Grand Rounds | Drs. Zimmerman and Benjamin discuss the ABC Science Collaborative, which aims to unite science and schools for a data-driven solution to decision-making and implementation around mitigating COVID-19. |
| Back to School, It’s More Than Just a Trip to Target This Year: The ABC Science Collaborative | 10/16/2020 | Grand Rounds | Drs. Zimmerman and Benjamin discuss the ABC Science Collaborative, which aims to unite science and schools for a data-driven solution to decision-making and implementation around mitigating COVID-19. |
| October 12, 2020: NIH Collaboratory Welcomes 2 New PRISM Demonstration Projects to Address the Opioid Epidemic | 10/12/2020 | News article | The Collaboratory announces 2 new PRISM Demonstration Projects. |
| Pragmatic Trial of Higher vs. Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis (HiLo) (GR Slides 2020) | 10/9/2020 | Grand Rounds | Dr. Wolf presents an update on HiLo, an NIDDK-funded pragmatic trial testing which phosphate treatment target provides the best clinical outcomes for patients. |
| Pragmatic Trial of Higher vs. Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis (HiLo) (GR Video 2020) | 10/9/2020 | Grand Rounds | Dr. Wolf presents an update on HiLo, an NIDDK-funded pragmatic trial testing which phosphate treatment target provides the best clinical outcomes for patients. |
| ACP PEACE Study Redesign (Details) | 10/7/2020 | Study design paper | This document describes changes to the ACP PEACE stepped-wedge study design to address effects caused by the onset of COVID-19. |
| October 7, 2020: A Year Into Implementation, HiLo Shares an Update and Lessons Learned | 10/7/2020 | News article | News article about HiLo Grand Rounds. |
| October 6, 2020: Four PRISM Demonstration Projects Awarded Continuation from Planning to Implementation Phase | 10/6/2020 | News article | News article about the PRISM projects being awarded from continuation to planning phase. |
| Driving Toward Health Impact: Our Journey and Path Forward | 10/2/2020 | Grand Rounds | Dr. Cook presents highlights of PCORI’s 2.0 strategic plan to accelerate the impact on health care and patient outcomes. |