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Grand Rounds 54: 5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial (Slides)3/20/2025Grand Rounds/Webinars
(Slides) In this Grand Rounds, Malaz Boustani, MD, MPH, discusses transforming brain health with early detection of cognitive problems in the primary care setting using the 5-cog paradigm.
Grand Rounds 54: 5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial (Video)3/20/2025Grand Rounds/Webinars
(Video) In this Grand Rounds, Malaz Boustani, MD, MPH, discusses transforming brain health with early detection of cognitive problems in the primary care setting using the 5-cog paradigm.
Key Informants’ Perceptions of Telehealth Palliative Care for People Living with Dementia in Nursing Homes3/19/2025Publications/Articles
(Article) A pilot ePCT of a telehealth palliative care program for nursing home residents living with dementia explores implementation barriers and facilitators.
Nonpharmacological Pain Management for People with Dementia: A Scoping Review Mapping Research Gaps from a Pragmatic Lens3/7/2025Publications/Articles
(Article) A scoping review of research studies of nonpharmacological pain interventions use and effectiveness with people living with dementia.   Eighty one studies covering 24 interventions were reviewed and mapped to the 9 domains of the Readiness Assessment for Pragmatic Trials (RAPT) model to summarize and identify research gaps.
An educational intervention to promote central nervous system-active deprescribing in dementia: A pilot study3/1/2025Publications/Articles
(Article) Results from IMPACT-funded pilot trial assessing the implementation feasibility and preliminary effectiveness of a patient nudge intervention to prompt deprescribing among people living with dementia (PLWD)  with CNS-active  polypharmacy.
How Do Researchers Identify and Recruit Dementia Caregivers? A Scoping Review2/5/2025Publications/Articles
(Article) This scoping review aimed to capture the current methodology for identifying and recruiting dementia caregivers in clinical studies.
Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners2/3/2025Publications/Articles
(Article) Investigators conducted a qualitative study of interactions between pharmacists and 55 patient care partner dyads in a secondary analysis of a pilot study of a pharmacist-led deprescribing intervention for people living with dementia in primary care.
Grand Rounds 52: Improving Advance Care Planning for Seriously Ill Primary Care Patients: UC Health Care Planning Study (Slides)1/16/2025Grand Rounds/Webinars
(Slides) In this Grand Rounds, Rebecca Sudore, MD, and Anne Walling, MD, PhD, discuss the evolving Advance Care Planning (ACP) definition and research along with lessons learned from their ACP PCORI pragmatic randomized control trial.
Grand Rounds 52: Improving Advance Care Planning for Seriously Ill Primary Care Patients: UC Health Care Planning Study (Video)1/16/2025Grand Rounds/Webinars
(Video) In this Grand Rounds, Rebecca Sudore, MD, and Anne Walling, MD, PhD, discuss the evolving Advance Care Planning (ACP) definition and research along with lessons learned from their ACP PCORI pragmatic randomized control trial.
Comprehensive Dementia Care Models: State of the Science and Future Directions1/1/2025Publications/Articles
(Article) The current Annual State of the Science Review provides an overview of the current state of comprehensive dementia care models in the United States and relevant policies. Challenges and opportunities for nursing education, research, and implementation across the translational research continuum are also outlined.
Randomized in error in pragmatic clinical trials1/1/2025Publications/Articles
(Article) Differential exclusion in pragmatic clinical trials after randomization can lead to selection bias.  Under the potential outcomes framework, investigators evaluated the feasibility of using a Bayesian model to identify the randomized-in-error status and estimate the average treatment effect among participants not randomized in error.
Grand Rounds 51: COVID Vaccination among Medicare Beneficiaries: Findings from an IMPACT Supplement (Slides)12/19/2024Grand Rounds/Webinars
(Slides) In this Grand Rounds, Kaley Hayes, PharmD, PhD & Daniel Harris, PhD, MPH discuss the COVid VAXines Effects on the Aged (COVVAXAGE) database, which was the first project with NIA LINKAGE program (external data linkage to CMS data in NIA-funded projects); they walk through associated papers and lessons learned working with industry partners CVS and Walgreens.
Grand Rounds 51: COVID Vaccination among Medicare Beneficiaries: Findings from an IMPACT Supplement (Video)12/19/2024Grand Rounds/Webinars
(Video) In this Grand Rounds, Kaley Hayes, PharmD, PhD & Daniel Harris, PhD, MPH discuss the COVid VAXines Effects on the Aged (COVVAXAGE) database, which was the first project with NIA LINKAGE program (external data linkage to CMS data in NIA-funded projects); they walk through associated papers and lessons learned working with industry partners CVS and Walgreens.
"What Matters" in the Emergency Department: A Prospective Analysis of Older Adults' Concerns and Desired Outcomes12/1/2024Publications/Articles
(Article) Researchers performed a secondary analysis of a multicenter prospective observational study as part of the 4Ms framework identifying "What Matters" to older adults seeking emergency department care and to identify patient characteristics associated with meeting desired outcomes.
Developing a prediction model for cognitive impairment in older adults following critical illness11/29/2024Publications/Articles
(Article) Researchers developed and tested a machine learning model for identifying new cognitive impairment or dementia in older adults after critical illness using electronic health record (EHR) data. Findings indicate taht machine learning using EHR data can predict new CI or dementia at 1-year post ICU discharge with acceptable accuracy, but further studies are needed.
Screening for Cognitive Impairment in the Emergency Department: Agreement between Older Adult Patient- and Informant-Completed Ascertain Dementia 8 Tool11/24/2024Publications/Articles
(Article) Researchers conducted a prospective observational study to assess concordance between the Ascertain Dementia 8 (AD8) tool administered to emergency department patients over 65 compared to information provided by patient care partners.
Technology that CARES: Enhancing dementia care through everyday technologies11/7/2024Publications/Articles
(Article) Investigators provide a common language and conceptual structure to understand digital technology use in ADRD care. They describe the pathways by which researchers might develop and deploy technology, including via Cognitive offloading, Automation, Remote monitoring, Emotional/social support, and Symptom treatment (CARES) and highlight emerging issues in technology-based care research.
Variation in the time to complete the primary COVID-19 vaccine series by race, ethnicity, and geography among older US adults11/7/2024Publications/Articles
(Article) The researchers conducted an observational study using the COVVAXAGE database. Medicare beneficiaries who received the COVID-19 vaccine primary series (two doses) between 01/01/2021 and 12/31/2021 were included. Racial differences in the time between doses was assessed across levels of urbanicity using g-formula.  Most beneficiaries received their second COVID-19 vaccine on time. Racial disparities were observed and shown to vary in size by geographic area.
A mixed-methods examination of the acceptability of, CareMOBI, a dementia-focused mhealth app, among primary care providers11/5/2024Publications/Articles
(Article) The aim of this study was to examine the acceptability of CareMOBI in the primary care setting and identify factors contributing to the likelihood of adoption among primary care providers. CareMOBI (mhealth for Organization to Bolster Interconnectedness) is a user-centered mobile application that supports secure communication between adult day health centers, primary care providers, and family caregivers.
Reactions of clinical neuropsychologists to the Alzheimer's Association workgroup's draft diagnostic and staging criteria for Alzheimer's disease10/29/2024Publications/Articles
(Article) Researchers surveyed clinical neuropsychologists with expertise in dementia about the criteria for diagnosing and staging of Alzheimer's disease recently published by an Alzheimer's Association workgroup.
Grand Rounds 50: Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners (Slides)10/17/2024Grand Rounds/Webinars
(Slides)  In this Grand Rounds, Maggie Ramirez, PhD, MS, MS, and Rafael Samper-Ternent, MD, PhD, describe "Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners"
Grand Rounds 50: Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners (Video)10/17/2024Grand Rounds/Webinars
(Video)  In this Grand Rounds, Maggie Ramirez, PhD, MS, MS, and Rafael Samper-Ternent, MD, PhD, describe "Using Pilot Studies to Inform ePCTs in Hispanic/Latino People Living with Dementia and their Care Partners"
Emergency Department Visits Among Patients with Dementia Before and After Diagnosis10/14/2024Publications/Articles
(Article) This cohort study assesses changes in emergency department (ED) use among Medicare beneficiaries aged 65 years and older before and after receiving a diagnosis of dementia. Researcher used data from the Medicare Current Beneficiary Survey from 2015 to 2021 to identify sample of 1779 Medicare beneficiaries with incident dementia and 3558 matched comparators without dementia.
Technology-based instrumental activities of daily living in persons with Alzheimer's disease and related disorders10/10/2024Publications/Articles
(Article) The current study examined the applicability and diagnostic accuracy of technology-based Instrumental activities of daily living (iADLs) in those evaluated for Alzheimer's disease and related dementias (ADRD).
A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials10/8/2024Publications/Articles
(Article) Authors conducted a review of published small stepped-wedge cluster randomized trials to understand how and why they are used, and to characterize approaches used in their design and analysis.
Feasibility of Implementing Dementia Collaborative Coaching into Routine Care in Nursing Homes10/6/2024Publications/Articles
(Article) This study evaluated the feasibility of implementing Dementia Collaborative Coaching (DCC) into the routine workflow of speech-language pathologists (SLPs) working in nursing homes (NHs). DCC is an intervention delivered by SLPs to train nursing assistants (CNAs) in communication strategies to support people living with dementia (PLWD).
Exploring Family Caregivers' Likelihood of Adopting a Novel App That Connects Care Teams of Persons Living With Dementia: A Mixed-Methods Study10/5/2024Publications/Articles
(Article) The research involved a concurrent mixed-methods triangulation design to assess the acceptability and likely use of CareMOBI, a mHealth app prototype that aims to support improved care coordination and communication between care team members, among family caregivers of PLWD adopting app.
Alzheimer's disease biomarkers and the tyranny of treatment10/3/2024Publications/Articles
(Article) Authors reflect on the advanced in Alzheimer's disease treatment and the implications these advances have on both therapeutic and diagnostic options for people living with the disease.
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