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| Uncovering treatment effect heterogeneity in pragmatic gerontology trials | 1/31/2026 | Publications/Articles | (Article) This study demonstrates how embedding machine learning methods, such as BART, within a principled causal inference framework can offer deeper insights into trial data with complex features including truncation by death and clustering-key considerations in analyzing pragmatic gerontology trials. |
| Home Time as a Patient-Centered Outcome in Pragmatic Trials: Promise, Pitfalls, and the Path Forward | 1/15/2026 | Grand Rounds/Webinars | (Grand Rounds) January 2026 – Grand Rounds 62, Drs. Hanson, Kim, Ankuda, and Van Houtven discuss home time as a patient-centered outcome in pragmatic trials. |
| IMPACT Grand Rounds 59: Using pragmatic trials to Using pragmatic trials to address prescription safety in older patients with diabetes (Video) | 11/20/2025 | Grand Rounds/Webinars | Richard W. Grant, MD, MPH, is a research scientist at the Kaiser Permanente Division of Research, Kaiser Permanente Northern California and The Permanente Medical Group regional director of Research and Evaluation for Complex Needs presents an overview of 2 pragmatic trials he has conducted intended to address prescription safety in older patients with diabetes. |
| Housing characteristics of older adults with cognitive impairment | 10/28/2025 | Publications/Articles | (Article) Using the 2022 National Health and Aging Trends Study, the investigators conduct a cross-sectional study to ascertain the housing characteristics of community-living older adults with cognitive impairment and compare characteristics of those who lived alone versus with others. |
| Piloting the MIND at Home Dementia Care Navigation Program in primary care | 10/28/2025 | Publications/Articles | (Article) This study evaluated the feasibility and potential impact of adapting and implementing the MIND at Home Dementia Care Navigation Program (MIND at Home) into primary care practices at two large unique health systems in the United States. |
| Alignment of Minimum Data Set 3.0 Ratings With Staff Care Partner Reports of Symptoms of Distress for Nursing Home Residents | 10/27/2025 | Publications/Articles | (Article) This brief report examined the comparative endorsement of ratings of behavioral and emotional distress for NH residents by staff care partners and as reported in the MDS 3.0. Findings indicate that what direct staff care partners endorsed as symptoms of distress for residents did not align with MDS 3.0 endorsement in about one-half of the cases. |
| Deprescribing Central Nervous System-Active Medications among Community-Dwelling Older Adults with Dementia in Primary Care: A Feasibility Study | 10/22/2025 | Publications/Articles | (Article) Results of a feasibility study of a one-arm pilot study of a deprescribing intervention consisting of patient/care partner education and self-management materials and provider decision support in six primary care practices of an integrated healthcare system between February and August 2023. |
| Reply to: The Unseen Burden: Undiagnosed Hypoglycemia and the Need for CGM in Long-Term Geriatric Care | 10/17/2025 | Publications/Articles | (Article) IMPACT Pilot investigators reply to the recently published letter by Dr. Elpidio Santillo which reflects on the recent work by Munshi and team highlights the diagnostic blind spot of intermittent testing and underscores the urgent need for a shift towards continuous, real-time data to accurately manage blood glucose levels and prevent adverse outcomes in geriatric patients. |
| IMPACT Grand Rounds 58: Building the NEXT STEPs Network (Video) | 10/16/2025 | Grand Rounds/Webinars | Research Grant Core Associate Leader, Kathleen Unroe, MD, MHA, MS presents her teams experience building the NEXT STEPS Network. |
| Ambulatory Care Follow-Up and Fragmentation After Emergency Department Visits Among Older Adults | 9/25/2025 | Publications/Articles | (Article) This study aimed to characterize ambulatory care patterns among older adults discharged from the emergency department (ED).MethodsThis retrospective cohort study of 55,391 ED visits from the 2015-2021 Medicare Current Beneficiary Survey examined ambulatory follow-up within 7 and 30 days. |
| Designing stepped wedge cluster randomized trials with a baseline measurement of the outcome | 9/23/2025 | Publications/Articles | (Article) A systematic investigation into the possibility of addressing a baseline outcome measurement in designing cross-sectional SW-CRTs. Three linear mixed modeling approaches to adjust for the baseline outcome and derive the corresponding variance formula of the treatment effect estimator under each are provided. |
| Agreement Between Fingerstick Blood Glucose and Continuous Glucose Monitor Measures Among Long-Term Care Facility Residents | 8/2/2025 | Publications/Articles | (Article) A parallel study comparing the sensitivity and specificity of electronic health record-based fingerstick blood analysis compared to continuous glucose monitoring to detect episodes of hypocglycemia among residents of long-term care facilities. |
| Comparative Effectiveness of Two Methods for Assigning Care Coordinators to People Living with Dementia | 6/14/2025 | Publications/Articles | (Article) Investigators conducted a pragmatic clinical trial embedded in a Medicare accountable care organization to explore comparative effectiveness of two strategies for assigning care coordinators to people living with dementia and their caregivers. Findings indicate partial effectiveness for adding proactive outreach to usual care when assigning care coordinators to PLWD. |
| IMPACT Grand Rounds 57: Meta Lessons Learned from Pilot and Demonstration Projects Implementation (Video) | 6/12/2025 | Grand Rounds/Webinars | (Video) In Grand Rounds 57, Jennifer Sullivan, PhD, describes lessons learned from IMPACT Pilot and Demonstration Projects implementation data. |
| IMPACT Grand Rounds 57: Meta Lessons Learned from Pilot and Demonstration Projects Implementation (Slides) | 6/12/2025 | Grand Rounds/Webinars | (Slides) In Grand Rounds 57, Jennifer Sullivan, PhD, describes lessons learned from IMPACT Pilot and Demonstration Projects implementation data. |
| An Embedded Pragmatic Clinical Trial of the Individualized Positive Psychosocial Interaction (IPPI) Program | 6/12/2025 | Publications/Articles | (Article) Results paper describing outcomes of the associated IMPACT-funded pilot study testing the integration of the Individualized Positive Psychosocial Interaction program into nursing home care for people living with dementia in 7 NHs. |
| Invested Partner Feedback on Technology Assistance in Dementia (Tech-AiD) | 6/11/2025 | Publications/Articles | (Article) Investigators conducted a multimethod study to collect feedback from care partners and healthcare professionals about a manualized behavioral intervention called Technology Assistance in Dementia (Tech-AiD) intended to improve care of people living with Alzheimer's disease and related dementias while also reducing burden among care partners. |
| Enhancing Interpretation of Cognitive Changes in Alzheimer’s Intervention Trials: Application of Standardized Regression-Based Change Scores | 5/25/2025 | Publications/Articles | (Article) Investigators test the use of standardized regression-based (SRB) change indices to understand equivocal trial results in behavioral interventions. |
| Program of intensive support in emergency departments for care partners of cognitively impaired patients: A randomized controlled trial | 5/21/2025 | Publications/Articles | (Article) Results of a randomized controlled trial of the Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients (POISED) intervention, which was designed to identify cognitive impairment for patients at point of care in the ED, determine root causes for that ED visit, and apply an individualized post-ED care management plan for patients and care partners. Despite a lack of demonstrated effectiveness, POISED offers insights for future development. A strategy to improve ED care for persons living with cognitive impairment or dementia might focus on gathering more actionable information at discharge rather than by care management after discharge. |
| IMPACT Grand Rounds 56: Bridging Research and Practice: An Update from Real World Data Scholars (Slides) | 5/15/2025 | Grand Rounds/Webinars | (Slides) In Grand Rounds 56, the 2023 Real World Data Scholars, Jinying Chen, PhD, Kenneth Lam, MD, MAS, Lindsay White, PhD, and Yongkang Zhang, PhD, MS, presented on their research projects using the Long-Term Care (LTC) Data Cooperative dataset. |
| Incidence of Long COVID diagnoses in 3.6 million US Medicare beneficiaries with COVID-19 | 5/15/2025 | Publications/Articles | (Article) This cohort study of 3,588,671 Medicare beneficiaries with COVID-19 explores the incidence of Long COVID among older adults and whether that incidence varies across clinical subgroup and vaccination history. |
| IMPACT Grand Rounds 56: Bridging Research and Practice: An Update from Real World Data Scholars (Video) | 5/15/2025 | Grand Rounds/Webinars | (Video) In Grand Rounds 56, the 2023 Real World Data Scholars, Jinying Chen, PhD, Kenneth Lam, MD, MAS, Lindsay White, PhD, and Yongkang Zhang, PhD, MS, presented on their research projects using the Long-Term Care (LTC) Data Cooperative dataset. |
| Emergency Department Utilization Among Co-Residing Family Caregivers of Persons Living With Dementia | 5/10/2025 | Publications/Articles | (Article) Results from an observational cohort study of emergency department visits among caregivers of people living with dementia that live with the PLWD compared to the same of caregivers that do not live with the PLWD. |
| External Validation of a Proprietary Risk Model for One-Year Mortality in Community-Dwelling Adults 65 Years or Older | 4/29/2025 | Publications/Articles | (Article) Investigators conduct a retrospective cohort study examining the discrimination, calibration, and algorithmic fairness of the Epic End-of-Life Care Index (EOL-CI). The EOL-CI is a proprietary risk model for one-year mortality that is integrated into the electronic health record (EHR) at many health systems but to date there have been no external validation studies performed to examine its’ performance in community-dwelling populations. |
| Leveraging data, technology, and policy to address disparities for persons living with Alzheimer's disease and Alzheimer's disease related dementias | 4/29/2025 | Publications/Articles | (Article) Authors highlight important gaps and opportunities in work addressing disparities related to Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presented during Session 4: Disparities in Health Care Access, Utilization, and Quality, of the 2023 National Research Summit on Care, Services, and Supports for Persons Living with Dementia and Their Care Partners/Caregivers. |
| Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway | 4/21/2025 | Publications/Articles | (Article) Results of a pilot study which tested the feasibility of ED clinicians referring older adult patients identified through CI screening and direct clinician referral for outpatient cognitive evaluation. |
| Grand Rounds 55: Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT-Brain Health Assessment (TabCAT-BHA) (Slides) | 4/17/2025 | Grand Rounds/Webinars | (Slides) In this Grand Rounds, Katherine Possin, PhD, discusses "Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment (TabCAT-BHA)." TabCAT-BHA is a software platform owned by UCSF to provide diagnosis in MCI and dementia. |
| Grand Rounds 55: Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT-Brain Health Assessment (TabCAT-BHA) (Video) | 4/17/2025 | Grand Rounds/Webinars | (Video) In this Grand Rounds, Katherine Possin, PhD, discusses "Augmenting Nurse Support and Electronic Health Record (EHR) Integration for the Pragmatic Trial of the TabCAT Brain Health Assessment (TabCAT-BHA)." TabCAT-BHA is a software platform owned by UCSF to provide diagnosis in MCI and dementia. |