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Resource_Description
  
  
10/31/2025Grand RoundsPeter Margolis; Sarah Greene; Sean C. DowdyStanford University; University of Cincinnati; Mayo Clinic; Cincinnati Children's Hospital Medical Center; The National Academy of MedicineThe LHS Shared Commitments — All Treats, No TricksPeter Margolis, Sean Dowdy, and Sarah Greene discuss “The LHS Shared Commitments – All Treats, No Tricks.”
  
10/31/2025Grand RoundsPeter Margolis; Sarah Greene; Sean C. DowdyUniversity of Cincinnati; Cincinnati Children's Hospital Medical Center; Mayo Clinic; Stanford University; The National Academy of MedicineThe LHS Shared Commitments — All Treats, No TricksPeter Margolis, Sean Dowdy, and Sarah Greene discuss “The LHS Shared Commitments – All Treats, No Tricks.”
  
10/24/2025Grand RoundsRenato LopesDuke Clinical Research Institute; Duke University Health SystemPrevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF TrialDr. Renato Lopes discusses “Prevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF Trial.”
  
10/24/2025Grand RoundsRenato LopesDuke University Health System; Duke Clinical Research InstitutePrevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF TrialDr. Renato Lopes discusses “Prevention And Reduction of Adverse outcomes in Chagasic Heart failUre Trial Evaluation: The PARACHUTE-HF Trial.”
  
10/17/2025Grand RoundsKeith Marsolo; Charles BaileyUniversity of Pennsylvania; Children's Hospital of Philadelphia; Duke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Making Effective Use of Data Infrastructure in PCORnet®Drs. Charles Bailey and Keith Marsolo discuss “Making Effective Use of Data Infrastructure in PCORnet®.”
  
10/17/2025Grand RoundsCharles Bailey; Keith MarsoloUniversity of Pennsylvania; Children's Hospital of Philadelphia; Duke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Making Effective Use of Data Infrastructure in PCORnet®Drs. Charles Bailey and Keith Marsolo discuss “Making Effective Use of Data Infrastructure in PCORnet®.”
  
10/10/2025Grand RoundsJulie Fritz; Sebastian TongUniversity of Utah; University of WashingtonIntegrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health InitiativeDrs. Fritz and Tong discuss "Integrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health Initiative."
  
10/10/2025Grand RoundsJulie Fritz; Sebastian TongUniversity of Utah; University of WashingtonIntegrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health InitiativeDrs. Fritz and Tong discuss "Integrating the BeatPain Study With PRaCTICe, a New Network Research Hub of the CARE for Health Initiative."
  
10/3/2025Grand RoundsElisabetta TonetUniversitaria di FerraraMulti-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe TrialDr. Elisabetta Tonet discusses “Multi-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe Trial.”
  
10/3/2025Grand RoundsElisabetta TonetUniversitaria di FerraraMulti-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe TrialDr. Elisabetta Tonet discusses “Multi-Domain Rehabilitation for Older Patients With Myocardial Infarction: The PIpELINe Trial.”
  
9/26/2025Grand RoundsElizabeth Turner; Gregory Simon; Susan HuangKaiser Permanente Washington Health Research Institute; University of California, Irvine; Duke UniversitySignificance in ePCTs: P Values vs Decision-Maker PerspectivesDrs. Gregory Simon, Susan Huang, and Elizabeth Turner discuss “Significance in ePCTs: P Values vs Decision-Maker Perspectives.”
  
9/26/2025Grand RoundsElizabeth Turner; Gregory Simon; Susan HuangKaiser Permanente Washington Health Research Institute; University of California, Irvine; Duke UniversitySignificance in ePCTs: P Values vs Decision-Maker PerspectivesDrs. Gregory Simon, Susan Huang, and Elizabeth Turner discuss “Significance in ePCTs: P Values vs Decision-Maker Perspectives.”
  
9/19/2025Grand RoundsDenise van HoutUniversity Medical Center Utrecth, the NetherlandsHurdles for the Delivery of Clinical Trials: Insights From the REMAP-CAP Trial in EuropeDr. Denise van Hout discusses the factors that led to success and challenges in different REMAP-CAP study sites.
  
9/19/2025Grand RoundsDenise van HoutUniversity Medical Center Utrecth, the NetherlandsHurdles for the Delivery of Clinical Trials: Insights From the REMAP-CAP Trial in EuropeDr. Denise van Hout discusses the factors that led to success and challenges in different REMAP-CAP study sites.
  
9/5/2025Grand RoundsRobert CaliffDuke University School of MedicineThe Non-Learning Health SystemDr. Robert Califf discusses the non-learning health system.
  
8/22/2025Grand RoundsEmily O'BrienDuke Clinical Research Institute; Duke University School of Medicine; Patient-Centered Outcomes Research Institute (PCORI)Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical TrialsDr. Emily O’Brien discusses “Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical Trials.”
  
8/22/2025Grand RoundsEmily O'BrienPatient-Centered Outcomes Research Institute (PCORI); Duke University School of Medicine; Duke Clinical Research InstituteAvoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical TrialsDr. Emily O’Brien discusses “Avoiding the Fumble: Building on a Decade of Lessons from Pragmatic Clinical Trials.”
  
8/15/2025Grand RoundsTim Walsh; Chris Weir; Richard ParkerUniversity of EdinburghDexmedetomidine- or Clonidine-Based Sedation Compared with Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial – Addressing a Complex Clinical Question with Novel Integrated Methodological ApproachesProfessors Tim Walsh and Chris Weir and Research Fellow Richard Parker discuss the A2B trial of dexmedetomidine- or clonidine-based sedation compared with propofol for critically ill patients.
  
8/15/2025Grand RoundsTim Walsh; Chris Weir; Richard ParkerUniversity of EdinburghDexmedetomidine- or Clonidine-Based Sedation Compared with Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial – Addressing a Complex Clinical Question with Novel Integrated Methodological ApproachesProfessors Tim Walsh and Chris Weir and Research Fellow Richard Parker discuss the A2B trial of dexmedetomidine- or clonidine-based sedation compared with propofol for critically ill patients.
  
8/8/2025Grand RoundsA. Eden EvinsHarvard Medical School; Massachusetts General HospitalYouth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting SupportDr. Eden Evins discusses “Youth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting Support."
  
8/8/2025Grand RoundsA. Eden EvinsHarvard Medical School; Massachusetts General HospitalYouth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting SupportDr. A. Eden Evins discusses “Youth Nicotine Vaping Cessation: RCT of Varenicline Added to Remote Young Adult Lay Counselor Delivered Behavioral Cessation Support Vs. Texting Support."
  
8/1/2025Grand RoundsKenneth KehlDana-Farber Cancer InstituteClinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer ProgressionDr. Kenneth L. Kehl discusses “Clinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer Progression.”
  
8/1/2025Grand RoundsKenneth KehlDana-Farber Cancer InstituteClinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer ProgressionDr. Kenneth L. Kehl discusses “Clinical Trial Notifications Triggered by Artificial Intelligence-Detected Cancer Progression.”
  
7/18/2025Grand RoundsAdrian Hernandez; Christopher Lindsell; Karen Chiswell; Sara Calvert; Rebecca SullengerDuke Clinical Research Institute; Duke University School of Medicine; Clinical Trials Transformation Initiative (CTTI)State of Clinical Trials: An Analysis of ClinicalTrials.govAdrian Hernandez, Rebecca Sullenger, Sara Bristol Calvert, Karen Chiswell, and Christopher Lindsell discuss the state of clinical trials.
  
7/18/2025Grand RoundsAdrian Hernandez; Christopher Lindsell; Karen Chiswell; Sara Calvert; Rebecca SullengerDuke Clinical Research Institute; Duke University School of Medicine; Clinical Trials Transformation Initiative (CTTI)State of Clinical Trials: An Analysis of ClinicalTrials.govAdrian Hernandez, Rebecca Sullenger, Sara Bristol Calvert, Karen Chiswell, and Christopher Lindsell discuss the state of clinical trials.
  
7/11/2025Grand RoundsTrevor Lentz; Tyler CopeDuke Clinical Research Institute; Duke University; Veterans Health AdministrationNovel Approaches to Recruiting Clinical Sites for Embedded Pragmatic Clinical Trials: Insights from the AIM-Back TrialDr. Trevor Lentz and Tyler Cope discuss the novel approaches used for site recruitment in the AIM-back Trial.
  
7/11/2025Grand RoundsTrevor Lentz; Tyler CopeDuke Clinical Research Institute; Duke University; Veterans Health AdministrationNovel Approaches to Recruiting Clinical Sites for Embedded Pragmatic Clinical Trials: Insights from the AIM-Back TrialDr. Trevor Lentz and Tyler Cope discuss the novel approaches used for site recruitment in the AIM-back Trial.
  
6/27/2025Grand RoundsAmrita MukhopadhyayNYU Langone Health; New York University School of MedicineGR-Slides-06-27-25Dr. Amrita Mukhopadhyay discusses "Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)."
  
6/27/2025Grand RoundsAmrita MukhopadhyayNew York University School of Medicine; NYU Langone HealthBuilding Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)Dr. Amrita Mukhopadhyay discusses "Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations for Heart Failure (BETTER CARE-HF)."
  
6/20/2025Grand RoundsScott GarrisonUniversity of Alberta; Pragmatic Trials CollaborativeThe BedMed Trials: Does the Timing of Blood Pressure Medication Matter?Dr. Scott Garrison discusses the BedMed Trials: Does the Timing of Blood Pressure Medication Matter?
  
6/20/2025Grand RoundsScott GarrisonUniversity of Alberta; Pragmatic Trials CollaborativeThe BedMed Trials: Does the Timing of Blood Pressure Medication Matter?Dr. Scott Garrison discusses the BedMed Trials: Does the Timing of Blood Pressure Medication Matter?
  
6/13/2025Grand RoundsNancy Kass; Ruth Faden; Stephanie Morain; Stephanie MorainJohns Hopkins University; Johns Hopkins Berman Institute of BioethicsFit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical TrialsDrs. Morain, Kass, and Faden discuss “Fit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical Trials.”
  
6/13/2025Grand RoundsNancy Kass; Stephanie Morain; Stephanie Morain; Ruth FadenJohns Hopkins Berman Institute of Bioethics; Johns Hopkins UniversityFit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical TrialsDrs. Morain, Kass, and Faden discuss “Fit for Purpose: Improving the Ethical Oversight of Pragmatic Clinical Trials.”
  
6/6/2025Grand RoundsJonathan CaseyVanderbilt University; Pragmatic Clinical Care Research GroupThe REDCap Advanced Randomization Module: A Trial Innovation Network Project to Support the Needs of Modern TrialsDr. Jonathan D. Casey discusses the REDCap advanced randomization module: a trial innovation network project to support the needs of modern trials.
  
6/6/2025Grand RoundsJonathan CaseyVanderbilt University; Pragmatic Clinical Care Research GroupThe REDCap Advanced Randomization Module: A Trial Innovation Network Project to Support the Needs of Modern TrialsDr. Jonathan D. Casey discusses the REDCap advanced randomization module: a trial innovation network project to support the needs of modern trials.
  
5/30/2025Grand RoundsAnkeet BhattKaiser Permanente Northern California; Stanford UniversityEmbedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE TrialDr. Ankeet S. Bhatt discusses “Embedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE Trial.”
  
5/30/2025Grand RoundsAnkeet BhattKaiser Permanente Northern California; Stanford UniversityEmbedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE TrialDr. Ankeet S. Bhatt discusses “Embedding Randomization into Clinical Care in Learning Healthcare Systems: Insights From the KP-VACCINATE Trial.”
  
5/16/2025Grand RoundsAdrian Hernandez; Jeffrey SpaederDuke Clinical Research InstituteGrand Rounds May 16, 2025: Pivoting Clinical Trials Into a New and Evolving World (Jeffrey A. Spaeder, MD; Adrian F. Hernandez, MD, MHS)Drs. Jeffrey Spaeder and Adrian Hernandez discuss “Pivoting Clinical Trials Into a New and Evolving World.”
  
5/16/2025Grand RoundsAdrian Hernandez; Jeffrey SpaederDuke Clinical Research Institute; IQVIAGrand Rounds May 16, 2025: Pivoting Clinical Trials Into a New and Evolving World (Jeffrey A. Spaeder, MD; Adrian F. Hernandez, MD, MHS)Drs. Jeffrey Spaeder and Adrian Hernandez discuss “Pivoting Clinical Trials Into a New and Evolving World.”
  
5/2/2025Grand RoundsRoland RJ van KimmenadeRadboud University Medical CenterFluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP StudyDr. Roland RJ van Kimmenade discusses “Fluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP Study.”
  
5/2/2025Grand RoundsRoland RJ van KimmenadeRadboud University Medical CenterFluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP StudyDr. Roland RJ van Kimmenade discusses “Fluid REStriction in Heart failure versus liberal fluid UPtake: The FRESH-UP Study.”
  
4/25/2025Grand RoundsMing Tai-SealeUniversity of California, San DiegoAutomated Response Technology Integrated into EMR and Physician-Patient CommunicationDr. Ming Tai-Seale discusses “Automated Response Technology Integrated into EMR and Patient-Physician Communication.”
  
4/25/2025Grand RoundsMing Tai-SealeUniversity of California, San DiegoAutomated Response Technology Integrated into EMR and Physician-Patient CommunicationDr. Ming Tai-Seale discusses “Automated Response Technology Integrated into EMR and Patient-Physician Communication.”
  
4/18/2025Grand RoundsSanjit S. JollyMcMaster UniversityColchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 TrialDr. Sanjit S. Jolly discusses “Colchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 Trial.”
  
4/18/2025Grand RoundsSanjit S. JollyMcMaster UniversityColchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 TrialDr. Sanjit S. Jolly discusses “Colchicine and Spironolactone Post-MI — A Review of the Late-Breaking Results of the CLEAR OASIS 9 Trial.”
  
4/11/2025Grand RoundsJeremy M. ShefnerBarrow Neurological InstitutePridopidine in ALS: Results from the Healey Platform TrialDr. Jeremy M. Shefner discusses “Pridopidine in ALS: Results from the Healey Platform Trial.”
  
3/28/2025Grand RoundsAnivarya Kumar; Matthew EngelhardDuke University School of MedicineA Cross-Sectional Study of GPT-4–Based Plain Language Translation of Clinical Notes to Improve Patient Comprehension of Disease Course and ManagementAnivarya Kumar and Dr. Matthew Engelhard discuss a cross-sectional study of GPT-4–based plain language translation of clinical notes to improve patient comprehension of disease course and management.
  
3/28/2025Grand RoundsAnivarya Kumar; Matthew EngelhardDuke University School of MedicineA Cross-Sectional Study of GPT-4–Based Plain Language Translation of Clinical Notes to Improve Patient Comprehension of Disease Course and ManagementAnivarya Kumar and Dr. Matthew Engelhard discuss a cross-sectional study of GPT-4–based plain language translation of clinical notes to improve patient comprehension of disease course and management.
  
3/21/2025Grand RoundsAlexander J. "AJ" BloodBrigham and Women's Hospital; Harvard Medical SchoolGenerative Artificial Intelligence in Clinical Trials: A Driver of Efficiency and Democratization of CareDr. Alexander J. “AJ” Blood discusses “Generative Artificial Intelligence in Clinical Trials: A Driver of Efficiency and Democratization of Care.”
  
3/21/2025Grand RoundsAlexander J. "AJ" BloodHarvard Medical School; Brigham and Women's HospitalGenerative Artificial Intelligence in Clinical Trials: A Driver of Efficiency and Democratization of CareDr. Alexander J. “AJ” Blood discusses “Generative Artificial Intelligence in Clinical Trials: A Driver of Efficiency and Democratization of Care.”
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