Emergency Department Utilization Among Co-Residing Family Caregivers of Persons Living With Dementia | 5/10/2025 | Funded Investigator | (Article) Results from an observational cohort study of emergency department visits among caregivers of people living with dementia that live with the PLWD compared to the same of caregivers that do not live with the PLWD. |
External Validation of a Proprietary Risk Model for One-Year Mortality in Community-Dwelling Adults 65 Years or Older | 4/29/2025 | Funded Investigator | (Article) Investigators conduct a retrospective cohort study examining the discrimination, calibration, and algorithmic fairness of the Epic End-of-Life Care Index (EOL-CI). The EOL-CI is a proprietary risk model for one-year mortality that is integrated into the electronic health record (EHR) at many health systems but to date there have been no external validation studies performed to examine its’ performance in community-dwelling populations. |
Leveraging data, technology, and policy to address disparities for persons living with Alzheimer's disease and Alzheimer's disease related dementias | 4/29/2025 | Funded Investigator | (Article) Authors highlight important gaps and opportunities in work addressing disparities related to Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presented during Session 4: Disparities in Health Care Access, Utilization, and Quality, of the 2023 National Research Summit on Care, Services, and Supports for Persons Living with Dementia and Their Care Partners/Caregivers. |
Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway | 4/21/2025 | Funded Investigator | (Article) Results of a pilot study which tested the feasibility of ED clinicians referring older adult patients identified through CI screening and direct clinician referral for outpatient cognitive evaluation. |
"There Should Be A Nurse On Call”: Complex Care Needs of Low-Income Older Adults in Medicaid-Supported Assisted Living | 4/10/2025 | Funded Investigator | (Article) The objective of this study was to explore the complex care needs and serious illness communication challenges experienced by low-income older adults in Medicaid-supported assisted living. Methods: A qualitative secondary framework analysis was conducted on data from a parent qualitative study involving 17 residents aged 60 and older with serious illnesses at a Medicaid-supported facility in New York City. |
Key Informants’ Perceptions of Telehealth Palliative Care for People Living with Dementia in Nursing Homes | 3/19/2025 | Funded Investigator | (Article) A pilot ePCT of a telehealth palliative care program for nursing home residents living with dementia explores implementation barriers and facilitators. |
Nonpharmacological Pain Management for People with Dementia: A Scoping Review Mapping Research Gaps from a Pragmatic Lens | 3/7/2025 | Implementation Core | (Article) A scoping review of research studies of nonpharmacological pain interventions use and effectiveness with people living with dementia. Eighty one studies covering 24 interventions were reviewed and mapped to the 9 domains of the Readiness Assessment for Pragmatic Trials (RAPT) model to summarize and identify research gaps. |
An educational intervention to promote central nervous system-active deprescribing in dementia: A pilot study | 3/1/2025 | Funded Investigator | (Article) Results from IMPACT-funded pilot trial assessing the implementation feasibility and preliminary effectiveness of a patient nudge intervention to prompt deprescribing among people living with dementia (PLWD) with CNS-active polypharmacy. |
How Do Researchers Identify and Recruit Dementia Caregivers? A Scoping Review | 2/5/2025 | Health Care Systems Core | (Article) This scoping review aimed to capture the current methodology for identifying and recruiting dementia caregivers in clinical studies. |
Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners | 2/3/2025 | Funded Investigator | (Article) Investigators conducted a qualitative study of interactions between pharmacists and 55 patient care partner dyads in a secondary analysis of a pilot study of a pharmacist-led deprescribing intervention for people living with dementia in primary care. |
Randomized in error in pragmatic clinical trials | 1/1/2025 | Design and Statistics Core | (Article) Differential exclusion in pragmatic clinical trials after randomization can lead to selection bias. Under the potential outcomes framework, investigators evaluated the feasibility of using a Bayesian model to identify the randomized-in-error status and estimate the average treatment effect among participants not randomized in error. |
Comprehensive Dementia Care Models: State of the Science and Future Directions | 1/1/2025 | Funded Investigator | (Article) The current Annual State of the Science Review provides an overview of the current state of comprehensive dementia care models in the United States and relevant policies. Challenges and opportunities for nursing education, research, and implementation across the translational research continuum are also outlined. |
"What Matters" in the Emergency Department: A Prospective Analysis of Older Adults' Concerns and Desired Outcomes | 12/1/2024 | | (Article) Researchers performed a secondary analysis of a multicenter prospective observational study as part of the 4Ms framework identifying "What Matters" to older adults seeking emergency department care and to identify patient characteristics associated with meeting desired outcomes. |
Developing a prediction model for cognitive impairment in older adults following critical illness | 11/29/2024 | Design and Statistics Core | (Article) Researchers developed and tested a machine learning model for identifying new cognitive impairment or dementia in older adults after critical illness using electronic health record (EHR) data. Findings indicate taht machine learning using EHR data can predict new CI or dementia at 1-year post ICU discharge with acceptable accuracy, but further studies are needed. |
Screening for Cognitive Impairment in the Emergency Department: Agreement between Older Adult Patient- and Informant-Completed Ascertain Dementia 8 Tool | 11/24/2024 | Funded Investigator | (Article) Researchers conducted a prospective observational study to assess concordance between the Ascertain Dementia 8 (AD8) tool administered to emergency department patients over 65 compared to information provided by patient care partners. |
Technology that CARES: Enhancing dementia care through everyday technologies | 11/7/2024 | Funded Investigator | (Article) Investigators provide a common language and conceptual structure to understand digital technology use in ADRD care. They describe the pathways by which researchers might develop and deploy technology, including via Cognitive offloading, Automation, Remote monitoring, Emotional/social support, and Symptom treatment (CARES) and highlight emerging issues in technology-based care research. |
Variation in the time to complete the primary COVID-19 vaccine series by race, ethnicity, and geography among older US adults | 11/7/2024 | Funded Investigator | (Article) The researchers conducted an observational study using the COVVAXAGE database. Medicare beneficiaries who received the COVID-19 vaccine primary series (two doses) between 01/01/2021 and 12/31/2021 were included. Racial differences in the time between doses was assessed across levels of urbanicity using g-formula. Most beneficiaries received their second COVID-19 vaccine on time. Racial disparities were observed and shown to vary in size by geographic area. |
A mixed-methods examination of the acceptability of, CareMOBI, a dementia-focused mhealth app, among primary care providers | 11/5/2024 | Funded Investigator | (Article) The aim of this study was to examine the acceptability of CareMOBI in the primary care setting and identify factors contributing to the likelihood of adoption among primary care providers. CareMOBI (mhealth for Organization to Bolster Interconnectedness) is a user-centered mobile application that supports secure communication between adult day health centers, primary care providers, and family caregivers. |
Reactions of clinical neuropsychologists to the Alzheimer's Association workgroup's draft diagnostic and staging criteria for Alzheimer's disease | 10/29/2024 | Funded Investigator | (Article) Researchers surveyed clinical neuropsychologists with expertise in dementia about the criteria for diagnosing and staging of Alzheimer's disease recently published by an Alzheimer's Association workgroup. |
Emergency Department Visits Among Patients with Dementia Before and After Diagnosis | 10/14/2024 | Funded Investigator | (Article) This cohort study assesses changes in emergency department (ED) use among Medicare beneficiaries aged 65 years and older before and after receiving a diagnosis of dementia. Researcher used data from the Medicare Current Beneficiary Survey from 2015 to 2021 to identify sample of 1779 Medicare beneficiaries with incident dementia and 3558 matched comparators without dementia. |
Technology-based instrumental activities of daily living in persons with Alzheimer's disease and related disorders | 10/10/2024 | Funded Investigator | (Article) The current study examined the applicability and diagnostic accuracy of technology-based Instrumental activities of daily living (iADLs) in those evaluated for Alzheimer's disease and related dementias (ADRD). |
A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials | 10/8/2024 | Design and Statistics Core | (Article) Authors conducted a review of published small stepped-wedge cluster randomized trials to understand how and why they are used, and to characterize approaches used in their design and analysis. |
Feasibility of Implementing Dementia Collaborative Coaching into Routine Care in Nursing Homes | 10/6/2024 | Funded Investigator | (Article) This study evaluated the feasibility of implementing Dementia Collaborative Coaching (DCC) into the routine workflow of speech-language pathologists (SLPs) working in nursing homes (NHs). DCC is an intervention delivered by SLPs to train nursing assistants (CNAs) in communication strategies to support people living with dementia (PLWD). |
Exploring Family Caregivers' Likelihood of Adopting a Novel App That Connects Care Teams of Persons Living With Dementia: A Mixed-Methods Study | 10/5/2024 | Funded Investigator | (Article) The research involved a concurrent mixed-methods triangulation design to assess the acceptability and likely use of CareMOBI, a mHealth app prototype that aims to support improved care coordination and communication between care team members, among family caregivers of PLWD adopting app. |
Alzheimer's disease biomarkers and the tyranny of treatment | 10/3/2024 | Ethics and Regulation Core | (Article) Authors reflect on the advanced in Alzheimer's disease treatment and the implications these advances have on both therapeutic and diagnostic options for people living with the disease. |
Embedding Authorship Identity into a Portal-Based Agenda Setting Intervention to Support Older Adults and Care Partners | 10/1/2024 | Funded Investigator | (Article) This cross-sectional chart review study evaluated an adaptation to OurNotes, a portal-based pre-visit agenda setting questinnaire. The adaptation included a self-identification question to help clinicians interpret information by nonpatients of patients in a geriatric practice. |
Socioeconomic and medical determinants of state-level subjective cognitive decline in the United States | 10/1/2024 | | (Article) This study highlights critical links between subjective cognitive decline SCD and socioeconomic and medical determinants in adults aged ≥ 45 in the United States, including the prevalence of poverty, diabetes, and hypertension |
Executive Functions are Independently Associated with Cognitive Dispersion in HIV Disease | 9/17/2024 | Funded Investigator | |
A Pragmatic Approach to Identifying Goal-Concordant Care for Nursing Home Residents with Alzheimer’s Disease or Related Dementias | 9/16/2024 | Patient and Caregiver Relevant Outcomes Core | (Research Letter) Researcher team sought to develop an innovative pragmatic approach to identifying goal-concordant care among nursing home (NH) residents with ADRD using existing NH EHR data from one large NH chain as a first step towards operationalizing an outcome that can be used in pragmatic trials. |
Health equity in COVID-19 testing among patients of a large national pharmacy chain | 9/11/2024 | Funded Investigator | |