| Housing characteristics of older adults with cognitive impairment | 10/28/2025 | | (Article) Using the 2022 National Health and Aging Trends Study, the investigators conduct a cross-sectional study to ascertain the housing characteristics of community-living older adults with cognitive impairment and compare characteristics of those who lived alone versus with others. |
| Alignment of Minimum Data Set 3.0 Ratings With Staff Care Partner Reports of Symptoms of Distress for Nursing Home Residents | 10/27/2025 | Funded Investigator; Implementation Core | (Article) This brief report examined the comparative endorsement of ratings of behavioral and emotional distress for NH residents by staff care partners and as reported in the MDS 3.0. Findings indicate that what direct staff care partners endorsed as symptoms of distress for residents did not align with MDS 3.0 endorsement in about one-half of the cases. |
| Deprescribing Central Nervous System-Active Medications among Community-Dwelling Older Adults with Dementia in Primary Care: A Feasibility Study | 10/22/2025 | Funded Investigator | (Article) Results of a feasibility study of a one-arm pilot study of a deprescribing intervention consisting of patient/care partner education and self-management materials and provider decision support in six primary care practices of an integrated healthcare system between February and August 2023. |
| Reply to: The Unseen Burden: Undiagnosed Hypoglycemia and the Need for CGM in Long-Term Geriatric Care | 10/17/2025 | Funded Investigator | (Article) IMPACT Pilot investigators reply to the recently published letter by Dr. Elpidio Santillo which reflects on the recent work by Munshi and team highlights the diagnostic blind spot of intermittent testing and underscores the urgent need for a shift towards continuous, real-time data to accurately manage blood glucose levels and prevent adverse outcomes in geriatric patients. |
| Ambulatory Care Follow-Up and Fragmentation After Emergency Department Visits Among Older Adults | 9/25/2025 | Funded Investigator | (Article) This study aimed to characterize ambulatory care patterns among older adults discharged from the emergency department (ED).MethodsThis retrospective cohort study of 55,391 ED visits from the 2015-2021 Medicare Current Beneficiary Survey examined ambulatory follow-up within 7 and 30 days. |
| Designing stepped wedge cluster randomized trials with a baseline measurement of the outcome | 9/23/2025 | Design and Statistics Core | (Article) A systematic investigation into the possibility of addressing a baseline outcome measurement in designing cross-sectional SW-CRTs. Three linear mixed modeling approaches to adjust for the baseline outcome and derive the corresponding variance formula of the treatment effect estimator under each are provided. |
| Agreement Between Fingerstick Blood Glucose and Continuous Glucose Monitor Measures Among Long-Term Care Facility Residents | 8/2/2025 | Funded Investigator | (Article) A parallel study comparing the sensitivity and specificity of electronic health record-based fingerstick blood analysis compared to continuous glucose monitoring to detect episodes of hypocglycemia among residents of long-term care facilities. |
| Comparative Effectiveness of Two Methods for Assigning Care Coordinators to People Living with Dementia | 6/14/2025 | Funded Investigator | (Article) Investigators conducted a pragmatic clinical trial embedded in a Medicare accountable care organization to explore comparative effectiveness of two strategies for assigning care coordinators to people living with dementia and their caregivers. Findings indicate partial effectiveness for adding proactive outreach to usual care when assigning care coordinators to PLWD. |
| An Embedded Pragmatic Clinical Trial of the Individualized Positive Psychosocial Interaction (IPPI) Program | 6/12/2025 | Funded Investigator | (Article) Results paper describing outcomes of the associated IMPACT-funded pilot study testing the integration of the Individualized Positive Psychosocial Interaction program into nursing home care for people living with dementia in 7 NHs. |
| Invested Partner Feedback on Technology Assistance in Dementia (Tech-AiD) | 6/11/2025 | Funded Investigator | (Article) Investigators conducted a multimethod study to collect feedback from care partners and healthcare professionals about a manualized behavioral intervention called Technology Assistance in Dementia (Tech-AiD) intended to improve care of people living with Alzheimer's disease and related dementias while also reducing burden among care partners. |
| Enhancing Interpretation of Cognitive Changes in Alzheimer’s Intervention Trials: Application of Standardized Regression-Based Change Scores | 5/25/2025 | Funded Investigator | (Article) Investigators test the use of standardized regression-based (SRB) change indices to understand equivocal trial results in behavioral interventions. |
| Program of intensive support in emergency departments for care partners of cognitively impaired patients: A randomized controlled trial | 5/21/2025 | Funded Investigator | (Article) Results of a randomized controlled trial of the Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients (POISED) intervention, which was designed to identify cognitive impairment for patients at point of care in the ED, determine root causes for that ED visit, and apply an individualized post-ED care management plan for patients and care partners. Despite a lack of demonstrated effectiveness, POISED offers insights for future development. A strategy to improve ED care for persons living with cognitive impairment or dementia might focus on gathering more actionable information at discharge rather than by care management after discharge. |
| Incidence of Long COVID diagnoses in 3.6 million US Medicare beneficiaries with COVID-19 | 5/15/2025 | Funded Investigator | (Article) This cohort study of 3,588,671 Medicare beneficiaries with COVID-19 explores the incidence of Long COVID among older adults and whether that incidence varies across clinical subgroup and vaccination history. |
| Emergency Department Utilization Among Co-Residing Family Caregivers of Persons Living With Dementia | 5/10/2025 | Funded Investigator | (Article) Results from an observational cohort study of emergency department visits among caregivers of people living with dementia that live with the PLWD compared to the same of caregivers that do not live with the PLWD. |
| External Validation of a Proprietary Risk Model for One-Year Mortality in Community-Dwelling Adults 65 Years or Older | 4/29/2025 | Funded Investigator | (Article) Investigators conduct a retrospective cohort study examining the discrimination, calibration, and algorithmic fairness of the Epic End-of-Life Care Index (EOL-CI). The EOL-CI is a proprietary risk model for one-year mortality that is integrated into the electronic health record (EHR) at many health systems but to date there have been no external validation studies performed to examine its’ performance in community-dwelling populations. |
| Leveraging data, technology, and policy to address disparities for persons living with Alzheimer's disease and Alzheimer's disease related dementias | 4/29/2025 | Funded Investigator | (Article) Authors highlight important gaps and opportunities in work addressing disparities related to Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) presented during Session 4: Disparities in Health Care Access, Utilization, and Quality, of the 2023 National Research Summit on Care, Services, and Supports for Persons Living with Dementia and Their Care Partners/Caregivers. |
| Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway | 4/21/2025 | Funded Investigator | (Article) Results of a pilot study which tested the feasibility of ED clinicians referring older adult patients identified through CI screening and direct clinician referral for outpatient cognitive evaluation. |
| "There Should Be A Nurse On Call”: Complex Care Needs of Low-Income Older Adults in Medicaid-Supported Assisted Living | 4/10/2025 | Funded Investigator | (Article) The objective of this study was to explore the complex care needs and serious illness communication challenges experienced by low-income older adults in Medicaid-supported assisted living. Methods: A qualitative secondary framework analysis was conducted on data from a parent qualitative study involving 17 residents aged 60 and older with serious illnesses at a Medicaid-supported facility in New York City. |
| Key Informants’ Perceptions of Telehealth Palliative Care for People Living with Dementia in Nursing Homes | 3/19/2025 | Funded Investigator | (Article) A pilot ePCT of a telehealth palliative care program for nursing home residents living with dementia explores implementation barriers and facilitators. |
| Nonpharmacological Pain Management for People with Dementia: A Scoping Review Mapping Research Gaps from a Pragmatic Lens | 3/7/2025 | Implementation Core | (Article) A scoping review of research studies of nonpharmacological pain interventions use and effectiveness with people living with dementia. Eighty one studies covering 24 interventions were reviewed and mapped to the 9 domains of the Readiness Assessment for Pragmatic Trials (RAPT) model to summarize and identify research gaps. |
| An educational intervention to promote central nervous system-active deprescribing in dementia: A pilot study | 3/1/2025 | Funded Investigator | (Article) Results from IMPACT-funded pilot trial assessing the implementation feasibility and preliminary effectiveness of a patient nudge intervention to prompt deprescribing among people living with dementia (PLWD) with CNS-active polypharmacy. |
| How Do Researchers Identify and Recruit Dementia Caregivers? A Scoping Review | 2/5/2025 | Health Care Systems Core | (Article) This scoping review aimed to capture the current methodology for identifying and recruiting dementia caregivers in clinical studies. |
| Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners | 2/3/2025 | Funded Investigator | (Article) Investigators conducted a qualitative study of interactions between pharmacists and 55 patient care partner dyads in a secondary analysis of a pilot study of a pharmacist-led deprescribing intervention for people living with dementia in primary care. |
| Randomized in error in pragmatic clinical trials | 1/1/2025 | Design and Statistics Core | (Article) Differential exclusion in pragmatic clinical trials after randomization can lead to selection bias. Under the potential outcomes framework, investigators evaluated the feasibility of using a Bayesian model to identify the randomized-in-error status and estimate the average treatment effect among participants not randomized in error. |
| Comprehensive Dementia Care Models: State of the Science and Future Directions | 1/1/2025 | Funded Investigator | (Article) The current Annual State of the Science Review provides an overview of the current state of comprehensive dementia care models in the United States and relevant policies. Challenges and opportunities for nursing education, research, and implementation across the translational research continuum are also outlined. |
| "What Matters" in the Emergency Department: A Prospective Analysis of Older Adults' Concerns and Desired Outcomes | 12/1/2024 | | (Article) Researchers performed a secondary analysis of a multicenter prospective observational study as part of the 4Ms framework identifying "What Matters" to older adults seeking emergency department care and to identify patient characteristics associated with meeting desired outcomes. |
| Developing a prediction model for cognitive impairment in older adults following critical illness | 11/29/2024 | Design and Statistics Core | (Article) Researchers developed and tested a machine learning model for identifying new cognitive impairment or dementia in older adults after critical illness using electronic health record (EHR) data. Findings indicate taht machine learning using EHR data can predict new CI or dementia at 1-year post ICU discharge with acceptable accuracy, but further studies are needed. |
| Screening for Cognitive Impairment in the Emergency Department: Agreement between Older Adult Patient- and Informant-Completed Ascertain Dementia 8 Tool | 11/24/2024 | Funded Investigator | (Article) Researchers conducted a prospective observational study to assess concordance between the Ascertain Dementia 8 (AD8) tool administered to emergency department patients over 65 compared to information provided by patient care partners. |
| Technology that CARES: Enhancing dementia care through everyday technologies | 11/7/2024 | Funded Investigator | (Article) Investigators provide a common language and conceptual structure to understand digital technology use in ADRD care. They describe the pathways by which researchers might develop and deploy technology, including via Cognitive offloading, Automation, Remote monitoring, Emotional/social support, and Symptom treatment (CARES) and highlight emerging issues in technology-based care research. |
| Variation in the time to complete the primary COVID-19 vaccine series by race, ethnicity, and geography among older US adults | 11/7/2024 | Funded Investigator | (Article) The researchers conducted an observational study using the COVVAXAGE database. Medicare beneficiaries who received the COVID-19 vaccine primary series (two doses) between 01/01/2021 and 12/31/2021 were included. Racial differences in the time between doses was assessed across levels of urbanicity using g-formula. Most beneficiaries received their second COVID-19 vaccine on time. Racial disparities were observed and shown to vary in size by geographic area. |